Glow sticks blog

Glow sticks help Penn State scientists seize frogs

seerootoys01 | 30 April, 2018 11:53

Frogs and different amphibians are in decline in lots of locations all over, because of such components as local weather trade, habitat loss, and sickness, so scientists are extra intent than ever on counting those that stay. but the little critters may also be elusive 

This week, Pennsylvania State institution researchers mentioned they'd discovered an excellent approach to entice the animals: glow sticks.

Over two weeks in the spring of 2015, the community positioned dozens of the gentle-emitting devices in “funnel traps” on state game lands near the college’s leading campus in State college. The greenish, six-inch light sticks have been corresponding to what a trick-or-treater could wear across the neck on Halloween.

Penn State scientists found that glow sticks helped trap frogs, salamanders, and newts into funnel traps similar to this one — enabling for easier monitoring of the amphibian populations.

Traps equipped with glow sticks attracted several times the numbers of creatures that had been caught in unlit traps, the scientists pronounced in the journal Herpetological review. The species that seemed to respond probably the most turned into the japanese pink-noticed newt, with lit traps catching six times as many women and three times as many adult males as there have been within the unlit traps.

however the glow sticks also held a major appeal for 3 other species that were counted: the noticed salamander, the Jefferson’s salamander, and the wood frog 

The purpose the lights work so neatly isn't wholly clear. previous reports have found glow sticks attract amphibians of their more youthful, larval degrees because the lights also invite smaller creatures that they like to consume. however the Penn State look at was focused on adults all the way through breeding season, when feeding is not the leading merchandise on the agenda.

“I don’t understand that we really truly consider why, however for some motive they’re attracted to the glow sticks,” talked about David Miller, an assistant professor of flora and fauna inhabitants ecology at Penn State’s faculty of Agricultural Sciences.

He turned into joined on the study by means of Michael Antonishak, who was an undergraduate at the time of the trapping, and David Muñoz, a doctoral student in ecology. The trio caught almost 5."000 amphibians in the traps, tagged and photographed them, then set them free.

The traps have been positioned in “vernal” swimming pools — rain-fed our bodies of water that kind right through the springtime and dry out later within the 12 months.

The 4 species that the scientists measured are not in any instant chance in Pennsylvania, nonetheless it is essential to count them nevertheless. without baseline numbers for the creatures, researchers would no longer be in a position to tell if their populations rose or fell in the future.

And now that the glow-stick conception has been effectively demonstrated, the authors are hopeful it is going to prove beneficial for sampling many kinds of amphibians, including people that are in decline.

More interesting links

http://www.seerootoys.com/

http://seerootooys.blogspot.com/

http://www.wc.com.hk/forum/viewtopic.php?f=7&t=16223&p=90277

http://labradoodle-dogs.net/forums/16-general-chat/3261-doggy-kisses.html

 

Strange breakthrough at Seattle Children?s is life-altering for young boy

seerootoys01 | 19 April, 2018 10:23

Two-year-old, right. Hunter has become one of just 15 pediatric patients at Seattle Children's who have had Tumor Paint injected into their veins. Contributed

 

LISTEN: Strange breakthrough at Seattle Children's is life-altering for young boy

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It’s a medical breakthrough in the cancer field that sounds almost too strange to be true. An injectable substance derived from scorpion venom that makes tumors appear as green as a glow sticks.

 

The “Tumor Paint,” as it’s called, was recently used on a local boy to guide the way to a tumor embedded deep in his brain.

 

Two-year-old Hunter has become one of just 15 pediatric patients at Seattle Children’s who have had Tumor Paint injected into their veins.

 

College or childcare? Seattle charity makes choice easy

 

How he got there began back in December when Hunter’s parents noticed he’d developed an odd quirk.

 

“Watching him walk — it almost looked like he would just start to lean and fall. Part of me thought, ‘well he’s just a little off balance he’s just a 2-year-old,’ but we’re talking in a matter of three weeks it got progressively worse,” Hunter’s mom, Laura Coffman, said.

 

With the tipsiness came vomiting. So off to the doctor’s office in Maple Valley.

 

“She checked his ears, checked his eyes, checked his nose, she was checking everything. I was just watching her and everything was coming back just fine and so she couldn’t figure it out … she said just go to Seattle Children’s and go from there,” Coffman remembers.

 

It was at Seattle Children’s that doctors made that life-altering discovery that can make a parent feel like the ground has opened up beneath them. They found Hunter had a mass at the back of his brain. Tests confirmed it was cancer and cancer cells were speckled throughout his brain.

 

“It was pretty much the worst — if you can think how it spread — it was the worst prognosis for his age when we were looking up anything. Our doctor kept telling us ‘don’t look online,’” Coffman said.

 

Soon after the worst though came hope in the form of something called “Tumor Paint.” Which, as you can imagine from the perspective of already terrified parents, can be a tough sell based on the name alone.

 

“I couldn’t wrap my brain around what the doctor was talking about how it was going to make it ‘glow,’” Coffman said.

 

Two years ago, on the brink of the first human trials, I spoke with University of Washington Professor, Fred Hutch brain cancer researcher and Doctor Jim Olson, who invented Tumor Paint. He said it was luck that led him to a protein found in scorpion venom that, when combined with a “flashlight” molecule can make tumors glow for surgeons.

 

“It gives back a beautiful green glow that they see as an overlay over the typical scene that they see,” Olson said.

 

It’s not a cancer treatment. Rather it’s a tool to guide the way for surgeons so that they cut only the glowing tumor and not critical, healthy brain tissue.

 

It was an invention born out of a promise Olson made to an 11-year-old girl. A patient he lost to an especially deadly form of brain cancer.

 

“Before she died she asked if we would take her brain at the time that she died and create research tools to share with other scientists around the world so that kids in the future wouldn’t have to go through what she did,” Olson said.

 

That’s why we have Tumor Paint today, and why Hunter is here today, too. Coffman says her son’s surgery went better than expected.

 

“The surgery went amazing. Went a lot faster. It was about four to five hours he was in surgery when it was supposed to be about eight. The doctor came out, I was sure she was going to come out and say ‘we couldn’t get anything’ and, you know, she came out and said ‘I got everything, there might be a light film left over, but he’s going to have a fight of chemotherapy and radiation,’ so we felt really good at that point,” Coffman said.

 

Hunter underwent three rounds of intense chemotherapy starting in January and ending in May. Then, he went through 30 sessions of proton radiation at the end of June. All told, two weeks ago Hunter was given a scan and the two-year-old was declared in remission.

 

Laura, however briefly, allowed herself to play the ‘what if’ game. What if there wasn’t Tumor Paint?

 

“I started researching other children who had Medulloblastoma and I started seeing these children who survived but they had really harsh side effects. The medical staff said ‘yeah that’s from surgery.’ And here Hunter is jumping into a pool, learning, I feel like he’s way more advanced than we ever thought he’d be at this stage … I have to believe that this is something that is changing surgeries completely because Hunter is dong amazing,” Coffman said.

 

Dr. Amy Lee at Seattle Children’s was the surgeon on this case. Hunter’s oncologist is Dr. Sarah Leary. She said the hospital has used Tumor Paint on 15 pediatric patients so far. All of the cases are part of the safety study required by the FDA as one step of many to get the substance approved for wider use.

 

Dr. Olson — Tumor Paint’s inventor — says it’s too early to know when FDA approval can happen. “They call the shots,” to put it in his own words. He says Tumor Paint has been tested for skin cancer, adults and children with brain tumors, and teams are now studying its use for breast cancer.

 

Much of the research into Tumor Paint, which began in 2004, was paid for through a crowdfunding campaign called Project Violet. The crowdfunding was a necessary step as many entities that approve grants found the Tumor Paint idea too ‘far out’ to fund initially.

 

The fundraising continues on Oct. 12 at Optimism Brewery on Capitol Hill. Hunter’s family will be there.

 

 
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